Thrombin is an enzyme in blood that acts on the clotting factor fibrinogen to form fibrin, helping blood to clot. The thrombin time assesses the activity of fibrinogen.Most often, the prothrombin time is monitored if you are taking the blood-thinning medication warfarin. In this situation, the prothrombin time is expressed as an international normalized ratio (INR).
Your doctor may recommend a prothrombin time test prior to surgery if there is any concern about your blood’s ability to clot.
The prothrombin time test may also be performed to evaluate you for liver disease.







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